Titanium nitride - Exposure
Tests outside of organisms - in vitro
As part of the BMBF-funded project INOS, TiN nanoparticles were examined in the human cell lines A549 (lung), HaCaT (skin), and CaCo-2 (intestine). These in vitro tests showed a cytotoxic effect of the TiN particles, which turned out to vary depending on the cell line (utilizing concentrations up to 50 µg / ml over 3 hours and 3 days).more...
- INOS Research Report, to be requested from the TIB Hannover , Grant Label 030X0013.
Hyde GK et al., 2009, Biomedical Materials, 4, 025001.
Paschoal AL et al, 2003, Artif Organs, 27, 461-464.
- Van Raay JJAM et al., 1995, Journal of Materials Science: Materials in Medicine, 6, 80-84.
Tests on living organisms - in vivo
Both a skin irritation test on rabbits and an acute systemic toxicity test on mice resulted in no effects caused by TiN . The TiN solutions tested here are used for the coating of implants.more...
- Paschoal AL et al, 2003, Artif Organs, 27, 461-464.
General hazards - Epidemiology
Epidemiological data on TiN-nanoparticles are not available.
Exposure - Environment
Currently there are no studies known that deal with the environmental exposure of TiN nanoparticles.