Aluminum and aluminum oxide particles are taken up in the cells. They tend to agglomerate unless stabilised by means of additives.

 

The agglomerates, which can also be taken up in the cells, are found in vesicles, i.e. they do not occur freely in the cells and are practically never detected in the cell nucleus. The agglomerated particles can be detected by means of electron microscopy in the cell inclusions. The vesicle membrane protects the remaining cell components from the particles [1,2,3,4].

 

Literature arrow down

  1. NanoCare 2009, Final Scientific Report, ISBN 978-3-89746-108-6. (PDF-Document, 19 MB).
  2. Monteiro-Riviere, NA et al. (2010), J Appl Toxicol, 30(3): 276-285.
  3. Wagner, AJ et al. (2007), J Phys Chem B, 111(25): 7353-7359.
  4. Simon-Deckers, A et al. (2008), Toxicology, 253(1-3): 137-146.

 

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