In vivo studies showed that implants of bacterial nanocellulose cause no foreign object reaction.

 

There were no altered tissue structures (so-called fibrosis) or encapsulations (defence action of the body to isolate the foreign substance) or the formation of so-called giant cells around the implant [1]. In a study on mice it was shown that short-term inflammatory reactions could occur on and around the implant, which decreased with time (up to 12 months follow-up) or completely disappeared [2].

 

Literature arrow down

  1. Klemm, D et al. (2011), Angew Chem Int Ed Engl, 50(24): 5438-5466.
  2. Pértile, RA et al. (2011), J Biomater Sci Polym Ed 2011.

 

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