The inhalation of nanoclays causes only minimal and temporary lung damage.

 

The instillation of sepiolite nanoclays in the lungs of rats led to a temporary inflammation of the lungs only. No adverse effects on other organs were observed [1]. However, these nanoparticles caused the formation of multi-core giant cells (so-called giant cells). The biological significance of this observation, however, is still unclear. A study with workers of a plant for the production of sepiolite nanoclays has shown that the pulmonary function of workers who were exposed to a higher dust concentration was significantly worse [2].

 

Literature arrow down

  1. Warheit, DB et al. (2010), Toxicol Lett, 192(3): 286-293.
  2. McConnochie, K et al. (1993), Thorax, 48(4): 370-374

 

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