Currently, nanozeolites are being tested primarily for use as substrates in biomedical applications. So far, there are no scientific data available on the general hazards of synthetically engineered nanozeolites.

 

In biomedical applications, nanozeolites are being tested for usage in contrast agents for diagnostic imaging (CT, MRI), bone or tissue growth scaffolds, as well as carrier materials for various pharmaceutical products. As drug carriers, the pore size of the zeolite nanoparticles can be optimised for the later application or the active substance to be transported. These applications are currently being intensively researched and tested in cell culture and animal experiments [1-4].

 

Faujasite, a naturally occurring member of the zeolite family, is classified as non-critical or nontoxic. It is therefore often used in medicine as a carrier material or due to its good biocompatibility and high porosity as wound dressing materials [5,6].

Erionite, another naturally occurring member of the zeolite family, however causes causes astbest-like effects due to its fibrous structure and was therefore classified as carcinogenic in humans by the International Agency for Research on Cancer (IARC) [7,8].

 

In summary, synthetically produced nanozeolites are being tested as substrates for biomedical applications because of their good biocompatibility

 

 

Literature arrow down

  1. Georgieva, V et al. (2016). Micropor Mesopor Mat, 232 256-263.
  2. Kaur, B et al. (2015). Colloids Surf B Biointerfaces, 135 201-208.
  3. Costa, R et al. (2013). J Mater Sci Mater Med, 24(2): 395-403.
  4. Vilaca, N et al. (2013). Colloids Surf B Biointerfaces, 112 237-244.
  5. Ninan, N et al. (2014). Colloids Surf B Biointerfaces, 115 244-252.
  6. Ninan, N et al. (2013). ACS Appl Mater Interfaces, 5(21): 11194-11206.
  7. International Agency for Research on Cancer (Iarc); 1987; IARC MONOGRAPHS ON THE EVALUATION OF THE CARCINOGENIC RISK OF CHEMICALS TO HUMANS Silica and Sorne Silicates - VOLUME 42,
  8. International Agency for Research on Cancer (Iarc); 1987; Supplement 7 (1987) Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42,

 

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